Taurine 4 / edited by Laura Della Corte ... [et al.]
- 作者： International Taurine Symposium (1999 : Siena, Italy)
- 其他作者：
- 其他題名：
- Springer e-books
- Taurine four
- 出版： New York : Kluwer Academic/Plenum Publishers c2002
- 叢書名： Advances in experimental medicine and biology ; ;v. 483
- 主題： Taurine--physiology--Congresses. , Taurine--Physiological effect--Congresses.
- ISBN： 9780306468384 (electronic bk.) 、 9780306464478 (paper)
- URL：
電子書
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- 系統號： 005168979 | 機讀編目格式
館藏資訊
Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3μM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from .