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Diverse effects of hypoxia on tumor progression / edited by M. Celeste Simon
- 其他作者：
- 其他題名：
- Springer eBooks
- 出版： Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg 2010
- 叢書名： Current topics in microbiology and immunology ,v. 345
- 主題： Anoxemia , Cancer invasiveness. , Biomedicine. , Cancer Research. , Embryology. , Human physiology.
- ISBN： 9783642133299 (electronic bk.) 、 9783642133282 (paper)
- URL：
電子書
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讀者標籤：
- 系統號： 005176968 | 機讀編目格式
館藏資訊
Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression. Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though additional genetic and genomic changes with a net result that hypoxia promotes tumor progression and therapeutic resistance. Hypoxia promotes cancer progression by regulating various aspects of cancer biology, including radiotherapy resistance, metabolism, angiogenesis and invasion/migration
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