The chemokine system in experimental and clinical hematology / edited by Oystein Bruserud
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- Springer eBooks
- 出版： Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg 2010
- 叢書名： Current topics in microbiology and immunology ,v.341
- 主題： Chemokines , Hematology, Experimental. , Blood--diseases , Biomedicine. , Cancer Research. , Hematology
- ISBN： 9783642126390 (electronic bk.) 、 9783642126383 (paper)
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電子書
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- 系統號： 005177417 | 機讀編目格式
館藏資訊
The aim of the issue is to describe and explain the importance of the chemokine system in hematology. The chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation. The present reviews illustrate that chemokines can be involved in leukemogenesis. The chemokine system is also important both for the crosstalk between malignant cells and their neighbouring nonmalignant stromal cells (including endothelial cells) as well as for immunoregulation in patients treated with allogeneic stem cell transplantation. Thus, chemokines are important both for the pathogenesis and treatment of hematological diseases.