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Polyploidization and cancer / edited by Randy Y. C. Poon
- 其他作者：
- 其他題名：
- Springer eBooks
- 出版： New York, NY : Landes Bioscience and Springer Science+Business Media, LLC 2010
- 叢書名： Advances in experimental medicine and biology ; ,v.675
- 主題： Cancer--Genetic aspects. , Polyploidy. , Biomedicine. , Biomedicine general.
- ISBN： 9781441961990 (electronic bk.) 、 9781441961983 (paper)
- URL：
電子書
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讀者標籤：
- 系統號： 005178037 | 機讀編目格式
館藏資訊
Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.
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