Molecular basis of pulmonary disease : insights from rare lung disorders / edited by Francis X. McCormack, Ralph J. Panos, Bruce C. Trapnell
- 作者： McCormack, Francis X.
- 其他作者：
- 出版： New York : Humana c2010
- 叢書名： Respiratory medicine
- 主題： Lungs--Diseases--Molecular aspects. , Lung Diseases , Molecular biology. , Rare diseases.
- ISBN： 9781588299635 (hbk.) :: US$230.69 、 1588299635 (hbk.)
- 一般註：Includes bibliographical references and index
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讀者標籤：
- 系統號： 005181838 | 機讀編目格式
館藏資訊
The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Lung Disease: Insights from Rare Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy to read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one titrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Lung Disease: Insights from Rare Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.
內容註
Clinical approach to rare lung diseases Clinical trials for rare lung diseases Idiopathic and familial pulmonary arterial hypertension Lymphangioleiomyomatosis Autoimmune pulmonary alveolar proteinosis Mutations in surfactant protein C and interstitial lung disease Hereditary haemorrhagic telangiectasia Hermansky-Pudlak Syndrome Alpha-1 antitrypsin deficiency Marfan syndrome Surfactant deficiency disorders : SP-B and ABCA3 Pulmonary capillary hemangiomatosis Anti-glomerular basement disease : Goodpasture's Syndrome Primary ciliary dyskinesia Pulmonary alveolar microlithiasis Cystic fibrosis Pulmonary Langerhans' cell histiocytosis : advances in the understanding of a true dendritic cell lung disease Sarcoidosis Scleroderma lung disease