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Molecular biology of cancer : mechanisms, targets, and therapeutics / Lauren Pecorino
- 作者： Pecorino, Lauren
- 出版： Oxford : Oxford University Press 2012
- 主題： Cancer--Molecular aspects. , Cancer cells. , Neoplasms--etiology , Antineoplastic Agents--therapeutic use. , Cell Transformation, Neoplastic--genetics. , Molecular Biology--methods , Neoplasms--genetics. , Neoplasms--therapy.
- 版本：3rd ed.
- ISBN： 9780199577170 (pbk.) :: NT$1550 、 019957717X (pbk.)
- 一般註：Includes bibliographical references and index
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讀者標籤：
- 系統號： 005206946 | 機讀編目格式
館藏資訊
摘要註
Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents
內容註
DNA structure and stability : mutations versus repair -- Regulation of gene expression -- Growth factor signaling and oncogenes -- The cell cycle -- Growth inhibition and tumor suppressor genes -- Apoptosis -- Stem cells and differentiation -- Metastasis -- The immune system, infections, and inflammation -- Nutrients, hormones, and gene interactions -- The cancer industry : drug development, pharmocogenomics, and clinical trial design -- Cancer in the future : focus on cancer vaccines and technology
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