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Microbial pathogenesis : infection and immunity / [edited by] Uday Kishore, Annapurna Nayak

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摘要註

"The book starts with dissecting mechanisms underlying viral immune evasion via exploiting the host complement system by vaccinia virus, and by modulating the type 1 interferon response by RNA viruses. Yet another chapter looks into how viroporins expressed by different families of viruses causing influenza A virus, SARS, hepatitis C and HIV interact with several cellular pathways. Understanding of these mechanisms can aid the development of novel potential anti-viral targets. The chapter on tuberculosis discusses the emerging importance of the innate immune mechanisms against Mycobacterium tuberculosis infection and latency. This book has a strong focus on fungal pathogenesis and immunity, starting with virulence and host factors that attain great importance in candidiasis and associated escape tricks of seriously opportunistic fungi. Two chapters on Aspergillus fumigatus elaborate on the pathogenic mechanisms: first discussing A. fumigatus-airway epithelium interaction, followed by fungal and host factors that are paramount in the development of allergic and invasive aspergillosis. In the subsequent chapter, there is a general discussion on the innate and adaptive immune responses against primary and opportunistic fungal pathogens"--Publisher's description

內容註

The complement system as a viral target for immune evasion / Ajitanuj Rattan, Rewati Kasbe, Jayati Mullick, and Arvind Sahu -- Modulation of type I interferon response by RNA viruses / Suchita Bhattacharyya -- Viroporins : differential functions at late stages of viral life cycles / Francois Kien, Huailiang Ma, Stefan Diaz Gaisenband, and Beatrice Nal -- Mycobacterium tuberculosis : innate immune recognition and persistence / Munirah Abdul-Aziz and Anthony G. Tsolaki -- Candida and candidiasis / Thomas Hofken -- Mechanisms of pathogenesis of aspergillosis / Savneet Kaur, Kavita Kale, Taruna Madan, and P. Usha Sarma -- Airway epithelium interactions with aspergillus fumigatus / Neelkamal Chaudhary -- Anti-fungal innate and adaptive immune responses / Uday Kishore, Suhair M. Abozaid, and Mohammed N. Al-Ahdal -- Host-pathogen interaction in malaria and trypanosomiasis / Janez Ferluga, Annapurna Nayak, and Uday Kishore -- The host pathogen interaction and immunomodulation during leishmaniasis / Surajit Bhattacharjee and Arijit Bhattacharya -- Immune responses induced by parasitic worms / Janez Ferluga, Lubna Kouser, and Uday Kishore -- Pathogenic persistence and evasion mechanisms in schistosomiasis / Annapurna Nayak and Uday Kishore -- Transmissible spongiform encephalopathies -- passage from gut to brain / Daniel A. Mitchell

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