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Extraskeletal effects of Vitamin D : a clinical guide / Emilia Pauline Liao, editor

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摘要註

While the skeletal effects of vitamin D are well-documented, the role and importance of vitamin D outside of bone health has not been well-established. Vitamin D receptors are located in nearly every tissue of the body, and low levels of vitamin D are associated with a range of various diseases. This book provides an in-depth examination of these extraskeletal effects of vitamin D and the associations between vitamin D deficiency and various disease states. Beginning with a review of the biochemistry and physiology of vitamin D, subsequent chapters investigate its relationship to autoimmune and infectious diseases, various forms of cancer, endocrine issues such as diabetes, obesity and reproductive function, cardiovascular disease and muscle weakness. Concluding chapters discuss the role of vitamin D in neurological disorders, including Alzheimer's Disease, and cognitive function

內容註

Intro; Series Editor Foreword; Preface; Contents; Contributors; Chapter 1: Vitamin D Biochemistry and Physiology; Introduction; Vitamin D Production; Vitamin D Metabolism; Transport of Vitamin D Metabolites in the Blood and Their Cellular Uptake; Vitamin D Mechanism of Action; Vitamin D Regulation of Cellular Function; Classic Vitamin D Target Tissues; Nonclassic Vitamin D Target Tissues; Regulation of Proliferation and Differentiation; Regulation of Hormone Secretion; Regulation of the Immune System; References; Chapter 2: Vitamin D and Autoimmune Diseases; Introduction; Vitamin D Deficiency Epidemiological Aspects: Vitamin D Status Among Patients with Active TB InfectionGenetic Aspects: V While the skeletal effects of vitamin D are well-documented, the role and importance of vitamin D outside of bone health has not been well-established. Vitamin D receptors are located in nearly every tissue of the body, and low levels of vitamin D are associated with a range of various diseases. This book provides an in-depth examination of these extraskeletal effects of vitamin D and the associations between vitamin D deficiency and various disease states. Beginning with a review of the biochemistry and physiology of vitamin D, subsequent chapters investigate its relationship to autoimmune and infectious diseases, various forms of cancer, endocrine issues such as diabetes, obesity and reproductive function, cardiovascular disease and muscle weakness. Concluding chapters discuss the role of vitamin D in neurological disorders, including Alzheimer's Disease, and cognitive function

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