Asthma : current perspectives on phenotypes, endotypes, and treatable traits / edited by Nikoletta Rovina.
- 其他作者：
- 其他題名：
- Journal of clinical medicine.
- 出版： Basel, Switzerland : MDPI 2020.
- 叢書名： Journal of clinical medicine
- 主題： Asthma. , Asthma--diagnosis. , Asthma--therapy.
- ISBN： 9783039438594 (hbk.) :: USD72.50
- 書目註：Includes bibliographical references.
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讀者標籤：
- 系統號： 005272319 | 機讀編目格式
館藏資訊
Asthma is a common complex and heterogeneous respiratory disease with an increasing prevalence in developed countries. Asthma is a disease consisting of different phenotypes that are driven by different mechanistic pathways (endotypes). The recognition of these phenotypes and endotypes is central to asthma management entailing prognostic and therapeutic implications. It is acknowledged that despite optimal treatment, many patients are poorly controlled, highlighting the need for phenotype-guided treatments. In this context, the emergence of novel therapies (monoclonal antibody therapy, bronchial thermoplasty) is paving the way for personalized asthma therapy. A better understanding of disease pathogenesis may enable the identification of biomarkers, mediators, novel therapeutic targets, and treatable traits. Further molecular phenotyping or endotyping of asthma will be necessary to tailor new therapeutic strategies. The present Special Issue on Asthma aims to provide the current knowledge on phenotypes and endotypes in appreciating and managing the heterogeneous condition that is asthma.