Cell-based assays using iPSCs for drug development and testing / edited by Carl-Fredrik Mandenius, James A. Ross.
- 其他作者：
- 其他題名：
- Cell-based assays using induced pluripotent stem cells for drug development and testing
- Methods in Molecular Biology (Clifton, N.J.)
- Springer protocols (Series)
- 出版： New York, NY : Humana Press c2020.
- 叢書名： Methods in Molecular Biology,1994 , Springer protocols
- 主題： Stem cells. , Induced Pluripotent Stem Cells. , Biological Assay--methods. , Drug Development--methods.
- ISBN： 978-1-4939-9479-3 (pbk.) :: EUR119.99 、 1-4939-9479-4 (pbk.) 、 978-1-4939-9476-2 (hbk.) 、 1-4939-9476-X (hbk.)
- 書目註：Includes bibliographical references and index.
-
讀者標籤：
- 系統號： 005272499 | 機讀編目格式
館藏資訊
The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study.
摘要註
"The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study."--Back cover.